Can I Run Devil May Cry 5 on a AMD Radeon RX 6600?

Devil May Cry 5
Yes — at lower settings

AMD Radeon RX 6600 · Gaming score 32/100 · Recommended GPU ≈ 50/100

Yes, but tune your settings. The AMD Radeon RX 6600 clears the minimum graphics requirement for Devil May Cry 5 but sits below the recommended card, so plan on Low–Medium settings (and upscaling) for a steady frame rate.

Estimated performance with a AMD Radeon RX 6600

ResolutionEstimated FPSSuggested settings
1080p30-45 FPSLow
1440pBelow 30 FPSNot recommended
4KBelow 30 FPSNot recommended

Estimates assume a balanced CPU and no GPU bottleneck. For a precise number including your exact CPU and upscaling, use the FPS Estimator.

Devil May Cry 5 system requirements

ComponentMinimumRecommended
CPUIntel® Core™ i5-4460, AMD FX™-6300, or betterIntel® Core™ i7-3770, AMD FX™-9590, or better
GPUNVIDIA® GeForce® GTX 760 or AMD Radeon™ R7 260x with 2GB Video RAM, or betterNVIDIA® GeForce® GTX 1060 with 6GB VRAM, AMD Radeon™ RX 480 with 8GB VRAM, or better
RAM8 GB8 GB
Storage35 GB35 GB

Should you upgrade?

If you want higher frame rates or to play at 1440p/4K in Devil May Cry 5, a faster card helps. Compare the AMD Radeon RX 6600 against alternatives on our GPU tier list, pair it sensibly with the bottleneck calculator, or see our best GPU picks for 2026.

Check current price & availability:

Check AMD Radeon RX 6600 price

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Frequently Asked Questions

Can the AMD Radeon RX 6600 run Devil May Cry 5?
Yes – at lower settings. The AMD Radeon RX 6600 passes the minimum GPU but not the recommended one, so Low–Medium settings are the sweet spot.

What FPS will I get in Devil May Cry 5 with a AMD Radeon RX 6600?
As a rough estimate, expect 30-45 FPS at 1080p (Low settings), dropping at 1440p and 4K. For a tuned estimate including your CPU and upscaling, use our free FPS Estimator.

How can I get more FPS in Devil May Cry 5?
Lower the heaviest settings (shadows, volumetrics, ray tracing), enable DLSS/FSR upscaling, cap background apps, and keep GPU drivers current. Our settings and optimization guides walk through each step.

Want to test a different setup? Try the full Can I Run It tool, estimate frames with the FPS Estimator, or view the full Devil May Cry 5 requirements page.